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Active and passive Immunotherapy

Active and Passive Immunotherapy

Now, the latest advances in allergy therapy involve the use of SLIT, sub-lingual Immunotherapy, the FDA-approved PROVEN treatment for allergy sufferers WITHOUT STEROIDS, ANTI-ALLERGIC & ANTI-INFLAMMATORY medicines. The Cochrane Collaboration, the world’s most-trusted international organization dedicated to reviewing healthcare treatments, recently concluded allergy drop immunotherapy significantly reduced allergy symptoms and use of allergy medications. ALLERGY TESTING IS ESSENTIAL!!! Allergy testing is important to guide Immunotherapy. Allergen Immunotherapy may be especially beneficial when avoidance and medications no longer control the patient's symptoms. WHAT IS SUBLINGUAL IMMUNOTHERAPY? Immunotherapy treats the cause of allergies by giving small doses of what a person is allergic to, which increases "immunity” or tolerance to the allergen and reduces the allergic symptoms. Thus, Immunotherapy is designed to build the body’s defences toward the range of allergens the patient has sensitivity to. The allergen is introduced into the body in small quantities, which are slowly increased to slightly larger quantities, and the body produces a better defence. In this way, Immunotherapy modulates the body into building a better defence against a trigger, such as wheat or dust or fungus. Unlike injection Immunotherapy, which is given as shots, Sublingual Immunotherapy is given as drops under the tongue. HOW DOES THE PROCESS WORK? The first step is to confirm a patient’s allergies through allergy testing. Then, a custom-mixed vial of drops is prepared for the patient. The patient takes drops under the tongue daily. During the first four months, called the “escalation phase,” the dosage is gradually increased. After that, in the “maintenance phase,” the patient takes the same dose of drops each day. IS SUBLINGUAL IMMUNOTHERAPY SAFE? It is very safe, for both adults and children. Patients take the drops in the convenience of their own homes instead of going to the doctor’s office every week for anti-allergy injections. The World Health Organization (WHO) has endorsed Sublingual Immunotherapy as a viable alternative to injection Immunotherapy. DOES IT WORK ? Many published scientific studies have shown that it significantly reduces allergy symptoms. HOW LONG MUST I CONTINUE THE TREATMENT? We recommend that patients keep using the drops for 18 months or longer so that the body will build up a lasting "Immunity." HOW DO I START SUBLINGUAL IMMUNOTHERAPY? Call Dr. Anita at +91 9766968834 for allergy testing and an evaluation to see if you are likely to benefit from Sublingual Immunotherapy. If you are, you will be prescribed the Sublingual Immunotherapy. The vials take a weeks to prepare because these are customised to each patient. During therapy, when your last vial is half empty, please call our office to order your new vial. HOW LONG CAN I EXPECT THE EFFECTS OF ALLERGY DROPS TO LAST? A benefit of Immunotherapy whether allergy shots or allergy drops — is that it can alter the course of allergic disease by treating the root cause, not just the symptoms. Once tolerance is built, it can be permanent for many patients. Key studies have already been conducted to explore the long-lasting effect of allergy drops, including a 10-year study on children with asthma that demonstrated drops maintained effectiveness long after treatment stopped. But even the best treatments won’t work if you don’t stay with them. Like allergy shot treatment, it’s important to stay with allergy drop treatment until your doctor has determined treatment can be discontinued to give you the best chance of long-term effectiveness. Benefits of three times daily dosing We have observed a combination of clinical symptom improvements, reduced skin test reactivity, and decreases in specific IgE levels at low doses of sublingual immunotherapy given three times a day. In 1986, Drs. Scadding and Brostoff published a dust mite study using threshold dosing four times daily. This double-blind, cross-over design study showed improvement in 72% of patients after only two weeks of treatment. The past 15 years have produced studies with a wide variety of dosing regimens showing efficacy. In some studies, when higher concentrations of antigen were used, side effects increased without much additional benefit. Frequency of dosing has also ranged from once a week to multiple times per day. Several studies now suggest there is more than one mechanism that helps an individual develop tolerance to their allergens. High-dose intermittent administration of antigen, similar to the La Crosse Method Preseasonal Protocol, produces clonal deletion and/or anergy. The low-dose frequent administration (three times daily dosing) of antigen sublingually leads to active suppression. This approach is used with the La Crosse Method Inhalant and Food Allergen Protocols. Combining multi-antigen threshold dosing with pre-seasonal rush protocols has clinically given providers the ability to take advantage of both mechanisms to develop allergen tolerance in a wide variety of allergic patients. Multi-allergen inhalant threshold dosing can be provided for patients with multiple moderate to severe allergies to pollens, mites, animals and molds or with a history of anaphylaxis. The treatment level is tailored to the patient's skin or blood test results. Patients take a dose three times daily using a metered dispenser that delivers a precise amount of antigen. One bottle lasts 90 days. Patients who test positively to seasonal allergies and fit the safety profile may be recommended for this high dose seasonal allergen therapy eight weeks before the allergy season begins, and continue treatment into the season. This treatment is considered an add-on to year-round inhalant Sublingual Immunotherapy. Some patients find that adding pre-seasonal treatment to their year-round therapy can reduce the time it takes to complete their therapy. The safety and efficacy of allergy drops has been proven in Europe for over 30 years. In fact, the World Health Organization has endorsed allergy drops as “a viable alternative to injection therapy.” The safety of Sublingual Immunotherapy has also been studied. Research has shown that severe reactions with Sublingual Immunotherapy are three times less common than with conventional allergy injections. Furthermore, there has never been a life-threatening anaphylaxis reaction with allergy drops in over 30 years, and over 200 million doses.

Immunotherapy is a globally accepted and validated treatment for allergic rhinitis. This mode of treatment modulates the immunity of the patient and hence improves his / her ability to combat the efffects of allergens. It is a much better option than the continuous use of topical and systemic medications, which invariably have side effects in the long term. The immunotherapy is custom-designed individually for each patient and is administered orally.

Immunotherapy reduces the intensity and frequency of allergic attacks and is proven to significantly improve the quality of life. It also reduces the patient's dependence upon anti-histaminics and steroids.

What is sublingual immunotherapy?

Unlike most allergy drugs - which treat only symptoms - sublingual immunotherapy addresses the underlying cause of allergies. Allergy drops are administered in gradually increasing dosages until the patient develops a tolerance to the allergy-causing substance. What is an antigen? An antigen is an allergy-causing substance. Examples include dust, pollen, mold, insect venom and specific foods such as fish, wheat, corn and eggs.

What kind of allergies can be treated with allergy drops?

The benefit of sublingual immunotherapy is that a broad range of allergies, including those caused by dust mites, pollen, mold, animals, foods and chemicals, can be treated.

Who should take allergy drops?

Although most allergy sufferers can benefit from allergy drops, they're especially ideal for people who can't tolerate or don't respond to allergy shots, as well as people who are unable to commit to allergy shot therapy.

These people include: Infants and children* Asthmatics Highly sensitive people Those with chronic conditions including sinusitis People with food and mold (fungal) allergies People with multiple allergies including dust, pollen, animals *Allergy drops have proven especially helpful for children with eczema and recurrent ear infections, which often have underlying allergic causes. Research shows that many children with untreated eczema and allergies often develop asthma and other chronic conditions later in life, so treating them early can have life-long benefits and may prevent development of other allergies.

Are allergy drops safe? Is there research validating their effectiveness?

Allergy drops have been used around the world, and numerous studies validate both the safety and effectiveness. In fact, the World Health Organization has endorsed sublingual immunotherapy as a viable alternative to injection therapy. It has been recently concluded allergy drop immunotherapy significantly reduced allergy symptoms and use of allergy medications.

What are the advantages of allergy drops?

In addition to being a viable option for people of all ages, there are other advantages to allergy drops. Lower cost, fewer clinic visits. Compared to shots, allergy drops cost less and require fewer clinic visits. Most patients receiving allergy drops need only a few clinic visits the first year, and once every 6-12 months thereafter until visits are no longer needed. More convenient. You can take allergy drops at home or wherever you need to be, making it much easier to stay with your treatment. Less medication. Our patients report, and research confirms, that they typically need less medication to control symptoms after beginning allergy drops. Enjoy healthier days. The end benefit? Feeling better. Patients typically report fewer clinic visits, hospitalizations, and less lost time from work and school after taking drops consistently.

Why don't more patients receive allergy drops if they're so effective?

Allergy drops are widely accepted as an effective treatment throughout the world. In fact, 50-75 percent of allergy sufferers in southern Europe are treated with allergy drops. That acceptance is growing throughout the world, and is beginning to grow in the United States as the treatment becomes more widely available.

Where can I get allergy drops?

Interest is growing among physicians from around the country to offer sublingual immunotherapy for their patients, however there may not be a physician located directly in your city. However, one of the benefits to allergy drops versus allergy shots is the decreased need for office visits. Allergy drops can be administered from home, while physician follow up may vary from six to 12 month intervals depending on the symptoms and severity of your allergies.

What are the ingredients?

Each prescription is a custom solution for each patient according to the type and severity of allergy. Drop prescriptions contain concentrates of the allergen the patient is found to be allergic to upon testing. Typically, the antigens are put into a glycerin solution for stability. There are no additional preservatives added.

What is the treatment process?

The first step is to confirm a patient's allergies through allergy testing. Then, a custom-mixed vial of drops is prepared for the patient. The patient takes drops under the tongue daily. During the first four months, called the "escalation phase," the dosage is gradually increased. After that, in the "maintenance phase," the patient takes the same dose of drops each day.

How long will I need to take my drops?

Most patients take allergy drops each day for 1 to 2 years, but it varies according to the severity of their allergies, seasonality, and how compliant they are with treatment. Many patients can begin to see symptom improvement within a few weeks to months.

How Can I order allergy drops from you?
Allergy drop treatment requires a physician to dose and monitor your treatment progress. Allergy drops using our treatment approach are dosed and adjusted over time based on your allergy test results rather than a one-size-fits all treatment approach. This helps to ensure maximum safety and effectiveness for each patient while also helping to reduce the likelihood of treatment side effects that have been noted with other treatment approaches.

How long can I expect the effects of allergy drops to last?

A benefit of immunotherapy whether allergy shots or allergy drops - is that it can alter the course of allergic disease by treating the root cause, not just the symptoms. Once tolerance is built, it can be permanent for many patients. Key studies have already been conducted to explore the long-lasting effect of allergy drops, including a 10-year study on children with asthma that demonstrated drops maintained effectiveness long after treatment stopped. But even the best treatments won't work if you don't stay with them. Like allergy shot treatment, it's important to stay with allergy drop treatment until your doctor has determined treatment can be discontinued to give you the best chance of long-term effectiveness.